Recombinant human S100A2 protein
S100A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may act as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also play a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Recombinant human S100A2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
S100 calcium binding protein A2, CAN19, S100L
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
13.1 kDa (117aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Nagy N., et al. (2001) cell carcinoma migration. Lab. Invest. 81: 599-612.; ; El-Rifai W., et al. (2002) Cancer Res. 62: 6823-6826.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 30% glycerol, 0.2M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_005969
Uniprot Accession Number
P29034
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MCSSLEQALA VLVTTFHKYS CQEGDKFKLS KGEMKELLHK ELPSFVGEKV DEEGLKKLMG SLDENSDQQV DFQEYAVFLA LITVMCNDFF QGCPDRP
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