Recombinant human Sorcin/SRI protein

Sorcin, also known as SRI, is a 22-kDa calcium-binding protein initially identified in multidrug-resistant cells. SRI modulates excitation-contraction coupling in the heart and contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Recombinant human SRI protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Sorcin, 22 kDa protein, CP22, V19, SCN

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.1 kDa (221aa) confirmed by MALDI-TOF

Additionnal Information

SRI, Sorcin, 22 kDa protein, CP22, V19, SCN, ATGP0941-10 µg, ATGP0941-20 µg, ATGP0941-50 µg, ATGP0941-100 µg, ATGP0941-250 µg, ATGP0941-500 µg, ATGP0941-1 mg, ATGP0941-10, ATGP0941-20, ATGP0941-50, ATGP0941-100, ATGP0941-250, ATGP0941-500, ATGP0941-1

References & Citations

Landriscina M., et al. (2010) Cancer Res. 70 (16) :6577-86; ; Meyers MB., et al. (1995) J Biol Chem. 270 (44) :26411-8

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT, 0.1mM PMSF

Scientific Category

Signal Transduction

NCBI Accession Number

NP_003121

Uniprot Accession Number

P30626

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAYPGHP GAGGGYYPGG YGGAPGGPAF PGQTQDPLYG YFAAVAGQDG QIDADELQRC LTQSGIAGGY KPFNLETCRL MVSMLDRDMS GTMGFNEFKE LWAVLNGWRQ HFISFDTDRS GTVDPQELQK ALTTMGFRLS PQAVNSIAKR YSTNGKITFD DYIACCVKLR ALTDSFRRRD TAQQGVVNFP YDDFIQCVMS V