Recombinant human Sorcin/SRI protein
Sorcin, also known as SRI, is a 22-kDa calcium-binding protein initially identified in multidrug-resistant cells. SRI modulates excitation-contraction coupling in the heart and contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Recombinant human SRI protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Sorcin, 22 kDa protein, CP22, V19, SCN
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.1 kDa (221aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Landriscina M., et al. (2010) Cancer Res. 70 (16) :6577-86; ; Meyers MB., et al. (1995) J Biol Chem. 270 (44) :26411-8
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT, 0.1mM PMSF
Scientific Category
Signal Transduction
NCBI Accession Number
NP_003121
Uniprot Accession Number
P30626
Species
Human
AA Sequence
Frequently Asked Questions
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