Recombinant human SNRPD2 protein
SNRPD2 is a small nuclear ribonucleoprotein (snRNPs) that comprises the spliceosome in eukaryotes. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. Recombinant human SNRPD2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Small nuclear ribonucleoprotein polypeptide D2, Sm-D2, SMD2, SNRPD1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
15.6 kDa (138aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Lehmeier T. et al. (1995) Proc Natl Acad Sci u S A, 91:12317-21.; ; Lehmeier T. et al. (1991) Nucleic Acids Res 18: 6475-84.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaCl,1mM DTT
Scientific Category
Other
NCBI Accession Number
NP_004588.1
Uniprot Accession Number
P62316
Species
Human
AA Sequence
SLLNKPKSE MTPEELQKRE EEEFNTGPLS VLTQSVKNNT QVLINCRNNK KLLGRVKAFD RHCNMVLENV KEMWTEVPKS GKGKKKSKPV NKDRYISKMF LRGDSVIVVL RNPLIAGK
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