Recombinant human NUDT16L1/SDOS protein

NuDT16L1, also known Syndesmos, is a cytoplasmic protein that interacts specifically with the cytoplasmic domain of syndecan-4, and it co-localizes with syndecan-4 in focal contacts. This protein interacts with the focal adhesion adaptor protein paxillin. The binding of syndesmos to paxillin is direct, and these interactions are triggered by the activation of protein kinase C. Recombinant human NuDT16L1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Nudix hydrolase 16 like 1, Tudor-interacting repair regulator protein, NUDT16-like protein 1, Protein syndesmos, Nudix-type motif 16-like 1, SDOS, TIRR

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

25.5 kDa (231aa) confirmed by MALDI-TOF

Additionnal Information

NUDT16L1, Protein syndesmos, MGC11275, SDOS, ATGP0934-10 µg, ATGP0934-20 µg, ATGP0934-50 µg, ATGP0934-100 µg, ATGP0934-250 µg, ATGP0934-500 µg, ATGP0934-1 mg, ATGP0934-10, ATGP0934-20, ATGP0934-50, ATGP0934-100, ATGP0934-250, ATGP0934-500, ATGP0934-1

References & Citations

Denhez F. et al. (2002) J. Biol. Chem. 277:12270-4.; ; Baciu PC. et al. (2000) J Cell Sci. 113:315-24.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Enzymes & Proteases

NCBI Accession Number

NP_115725

Uniprot Accession Number

Q9BRJ7

Species

Human

AA Sequence

MSTAAVPELK QISRVEAMRL GPGWSHSCHA MLYAANPGQL FGRIPMRFSV LMQMRFDGLL GFPGGFVDRR FWSLEDGLNR VLGLGLGCLR LTEADYLSSH LTEGPHRVVA HLYARQLTLE QLHAVEISAV HSRDHGLEVL GLVRVPLYTQ KDRVGGFPNF LSNAFVSTAK CQLLFALKVL NMMPEEKLVE ALAAATEKQK KALEKLLPAS S