Recombinant human MESDC2 protein
MESDC2, also known as Mesoderm development candidate 2, is required for formation of the primitive streak and mesoderm during embryogenesis. This protein binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression. Recombinant human MESDC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
LDLR chaperone MESD, BOCA, KIAA0081, MESD
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.9 kDa (222aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Kohler C, et al. (2006) . J Struct Funct Genomics, 7:131-8.; ; Wines ME., et al. (2001) . Genomics., 72:88-98.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_055969
Uniprot Accession Number
Q14696
Species
Human
AA Sequence
Frequently Asked Questions
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