Recombinant human ERH protein
ERH, also known as enhancer of rudimentary homolog, is a ubiquitously expressed transcriptional coregulator that is highly conserved among eukaryotes. It may play a role in cell cycle regulation and pyrimidine biosynthesis. It has two casein kinase II phosphorylation sites that are thought to disrupt the ability of ERH to dimerize. Recombinant human ERH protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Enhancer of rudimentary homolog, DROER, FLJ27340
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
14.6 kDa (127aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Pogge von Strandmann E., et al. (2001) . Biol. Chem., 382: 1379-1385.; ; Wan C., et al. (2005) . Biochemistry., 44: 5017-5023.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.1M NaCl
Scientific Category
Cell Cycle
NCBI Accession Number
NP_004441
Uniprot Accession Number
P84090
Species
Human
AA Sequence
MGSMSHTILL VQPTKRPEGR TYADYESVNE CMEGVCKMYE EHLKRMNPNS PSITYDISQL FDFIDDLADL SCLVYRADTQ TYQPYNKDWI KEKIYVLLRR QAQQAGK
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