Recombinant human CCL14/HCC-1 protein

CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1alpha. It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1 (9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5. Recombinant human CCL14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Product Specifications

Product Name Alternative

SY14, Small-inducible cytokine A14, SCYL2, SCYA14, NCC-2, NCC2, MCIF, HCC-3, HCC-1, FLJ16015, CKb1, Chemokine CC-1/CC-3, Chemokine (C-C motif) ligand 14, CC-3, CC-1, C-C motif chemokine 14

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

10.9 kDa (95aa) confirmed by MALDI-TOF

Additionnal Information

CCL14a, HCC1, C-C motif chemokine 14, CC-1, CC-3, CKb1, FLJ16015, HCC-1, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14, Chemokine (C-C motif) ligand 14, ATGP0930-10 µg, ATGP0930-20 µg, ATGP0930-50 µg, ATGP0930-100 µg, ATGP0930-250 µg, ATGP0930-500 µg, ATGP0930-1 mg, ATGP0930-10, ATGP0930-20, ATGP0930-50, ATGP0930-100, ATGP0930-250, ATGP0930-500, ATGP0930-1