Recombinant human BATF protein
BATF, also known as SFA2, is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. BATF is strongly expressed in mature T and B lymphocytes, and is up-regulated after transformation by human T-cell leukemia virus type I. BATF functions as a tissue-specific modulator of the AP-1 transcription complex in human cells. BATF also associates with IFP35, a leucine zipper protein that translocates to the nucleus following IFN treatment. Recombinant human BATF protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Basic leucine zipper transcriptional factor ATF-like, B-ATF, BATF1, SFA-2, SFA2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
16.2 kDa (145aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Quigley M., et al. (2010) Nat Med. 16 (10) :1147-51.; ; Betz BC., et al. (2010) J Exp Med. 207 (5) :933-42.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_006390.1
Uniprot Accession Number
Q16520
Species
Human
AA Sequence
MPHSSDSSDS SFSRSPPPGK QDSSDDVRRV QRREKNRIAA QKSRQRQTQK ADTLHLESED LEKQNAALRK EIKQLTEELK YFTSVLNSHE PLCSVLAAST PSPPEVVYSA HAFHQPHVSS PRFQP
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