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Recombinant human BATF protein

BATF, also known as SFA2, is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. BATF is strongly expressed in mature T and B lymphocytes, and is up-regulated after transformation by human T-cell leukemia virus type I. BATF functions as a tissue-specific modulator of the AP-1 transcription complex in human cells. BATF also associates with IFP35, a leucine zipper protein that translocates to the nucleus following IFN treatment. Recombinant human BATF protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Basic leucine zipper transcriptional factor ATF-like, B-ATF, BATF1, SFA-2, SFA2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

16.2 kDa (145aa) confirmed by MALDI-TOF

Additionnal Information

BATF, Basic leucine zipper transcriptional factor ATF-like, B-ATF, BATF1, SFA-2, SFA2, ATGP0929-10 µg, ATGP0929-20 µg, ATGP0929-50 µg, ATGP0929-100 µg, ATGP0929-250 µg, ATGP0929-500 µg, ATGP0929-1 mg, ATGP0929-10, ATGP0929-20, ATGP0929-50, ATGP0929-100, ATGP0929-250, ATGP0929-500, ATGP0929-1

References & Citations

Quigley M., et al. (2010) Nat Med. 16 (10) :1147-51.; ; Betz BC., et al. (2010) J Exp Med. 207 (5) :933-42.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_006390.1

Uniprot Accession Number

Q16520

Species

Human

AA Sequence

MPHSSDSSDS SFSRSPPPGK QDSSDDVRRV QRREKNRIAA QKSRQRQTQK ADTLHLESED LEKQNAALRK EIKQLTEELK YFTSVLNSHE PLCSVLAAST PSPPEVVYSA HAFHQPHVSS PRFQP

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