Recombinant human LYPLA2 protein

Acyl-protein thioesterase 2, also known LYPLA2, is lysophospholipase that acts on biological membranes to regulate the multifunctional lysophospholipids. This protein may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Recombinant human LYPLA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Acyl-protein thioesterase 2, APT-2, APT2, Lysophospholipase II, LPL-II, LysoPLA II

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

26.9 kDa (251aa) confirmed by MALDI-TOF

Additionnal Information

LYPLA2, Acyl-protein thioesterase 2, APT-2, APT2, Lysophospholipase II, LPL-II, LysoPLA II, ATGP0926-10 µg, ATGP0926-20 µg, ATGP0926-50 µg, ATGP0926-100 µg, ATGP0926-250 µg, ATGP0926-500 µg, ATGP0926-1 mg, ATGP0926-10, ATGP0926-20, ATGP0926-50, ATGP0926-100, ATGP0926-250, ATGP0926-500, ATGP0926-1

References & Citations

Fan J., et al. (2008) Int J Infect Dis. 12 (2) :143-51.; ; Wanq A., et al. (2000) Biochim Biophys Acta. 1484:207-14.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol,100 mM NaCl

Scientific Category

Metabolism

NCBI Accession Number

NP_009191.1

Uniprot Accession Number

O95372

Species

Human

AA Sequence

MCGNTMSVPL LTDAATVSGA ERETAAVIFL HGLGDTGHSW ADALSTIRLP HVKYICPHAP RIPVTLNMKM VMPSWFDLMG LSPDAPEDEA GIKKAAENIK ALIEHEMKNG IPANRIVLGG FSQGGALSLY TALTCPHPLA GIVALSCWLP LHRAFPQAAN GSAKDLAILQ CHGELDPMVP VRFGALTAEK LRSVVTPARV QFKTYPGVMH SSCPQEMAAV KEFLEKLLPP V