Recombinant human CAPS protein

Calcyphosine, also known as CAPS, is a calcium-binding protein containing four EF-hand domains. CAPS is initially identified as thyroid protein p24 that is found in several epithelium and in some cells of the central nervous system. It may play a role in the regulation of ion transport. In thyroid follicular cells, CAPS is synthesized and phosphorylated in response to stimulation by thyrotropin and cAMP agonists. Recombinant human CAPS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Calcyphosine, CAPS1, Calcyphosin

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

23.1 kDa (209aa) confirmed by MALDI-TOF

Additionnal Information

CAPS, Calcyphosine, CAPS1, Calcyphosin, ATGP0924-10 µg, ATGP0924-20 µg, ATGP0924-50 µg, ATGP0924-100 µg, ATGP0924-250 µg, ATGP0924-500 µg, ATGP0924-1 mg, ATGP0924-10, ATGP0924-20, ATGP0924-50, ATGP0924-100, ATGP0924-250, ATGP0924-500, ATGP0924-1

References & Citations

El Housni H, et al. (1997) Mol Cell Endocrinol. 135 (1) :93-7.; ; Halleux P, et al. (1998) J Chem Neuroanat. 15 (4) :239-50.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 100 mM NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_004049

Uniprot Accession Number

K7EL21

Species

Human

AA Sequence

MDAVDATMEK LRAQCLSRGA SGIQGLARFF RQLDRDGSRS LDADEFRQGL AKLGLVLDQA EAEGVCRKWD RNGSGTLDLE EFLRALRPPM SQAREAVIAA AFAKLDRSGD GVVTVDDLRG VYSGRAHPKV RSGEWTEDEV LRRFLDNFDS SEKDGQVTLA EFQDYYSGVS ASMNTDEEFV AMMTSAWQL