Recombinant human RERG protein
RERG is a 199 amino acid protein that localizes in the cytoplasm and belongs to the Ras subfamily of small GTPases. RERG is expressed in pancreas, liver, skin, lung, brain, kidney and heart tissue. It is critical mediators of diverse cell signaling pathways, including those leading to cell proliferation, cytoskeletal organization and secretion. Recombinant human RERG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ras-related and estrogen-regulated growth inhibitor, MGC15754
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
24.7 kDa (219aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Woodfield GW., et al. (2007) Cancer Res. 67 (18) :8439-43.; ; Finlin BS., et al. (2001) J Biol Chem. 276 (45) :42259-67.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 50% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_116307
Uniprot Accession Number
Q96A58
Species
Human
AA Sequence
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