Recombinant human RAB6B protein

RAB6B, also known as ras-related protein Rab-6B, belongs to Rab6 family of the small GTPase superfamily. The Rab6 subfamily consists of three different isoforms: Rab6A, Rab6A' and Rab6B. Both Rab6A and Rab6A' are ubiquitously expressed whereas Rab6B is predominantly expressed in brain. Rab6 is a key regulator in the retrograde transfer from endosomes via the Golgi to the ER and may function in retrograde tansport in neuronal cells. Recombinant human RAB6B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Ras-related protein Rab-6B, RAB6B member RAS oncogene family

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

25.6 kDa (228aa) confirmed by MALDI-TOF

Additionnal Information

RAB6B, Ras-related protein Rab-6B, RAB6B, member RAS oncogene family, ATGP0918-10 µg, ATGP0918-20 µg, ATGP0918-50 µg, ATGP0918-100 µg, ATGP0918-250 µg, ATGP0918-500 µg, ATGP0918-1 mg, ATGP0918-10, ATGP0918-20, ATGP0918-50, ATGP0918-100, ATGP0918-250, ATGP0918-500, ATGP0918-1

References & Citations

Wanschers B, et al. (2008), Cell Motil Cytoskeleton., 65:183-96.; ; Wanschers BF., et al. (2007) . Exp Cell Res. 313:3408-20.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_057661

Uniprot Accession Number

Q9NRW1

Species

Human

AA Sequence

MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNLNS FQQTSKWIDD VRTERGSDVI IMLVGNKTDL ADKRQITIEE GEQRAKELSV MFIETSAKTG YNVKQLFRRV ASALPGMENV QEKSKEGMID IKLDKPQEPP ASEGGCSC