Recombinant human CIB2 protein

CIB2 belongs to calcium and integrin-binding family. CIB2 may be a Ca2+-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunit (DNA-PKcs) . In skeletal muscle, CIB2 colocalizes with the integrin alpha7B subunit at the sarcolemma and at the neuromuscular and myotendinous junctions. CIB2 is closely related to CIB1. Recombinant human CIB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Calcium and integrin binding family member 2, KIP2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

23.8 kDa (207aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

CIB2, calcium and integrin binding family member 2, KIP2, ATGP0909-10 µg, ATGP0909-20 µg, ATGP0909-50 µg, ATGP0909-100 µg, ATGP0909-250 µg, ATGP0909-500 µg, ATGP0909-1 mg, ATGP0909-10, ATGP0909-20, ATGP0909-50, ATGP0909-100, ATGP0909-250, ATGP0909-500, ATGP0909-1

References & Citations

Yu Y., et al. (2009) Mol Biol Rep. 36 (7) :1799-809.; ; Hager M., et al. (2008) J Biol Chem. 5; ;283 (36) :24760-9.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 100 mM NaCl, 1mM PMSF

Scientific Category

Signal Transduction

NCBI Accession Number

NP_006374

Uniprot Accession Number

O75838

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGNKQTIFTE EQLDNYQDCT FFNKKDILKL HSRFYELAPN LVPMDYRKSP IVHVPMSLII QMPELRENPF KERIVAAFSE DGEGNLTFND FVDMFSVLCE SAPRELKANY AFKIYDFNTD NFICKEDLEL TLARLTKSEL DEEEVVLVCD KVIEEADLDG DGKLGFADFE DMIAKAPDFL STFHIRI