Recombinant human DCUN1D1 protein

DCuN1D1, also known as DCN1-like protein 1, is involved in the malignant transformation of squamous cell lineage. This protein regulates Gli1, a key regulator of the hedgehog (HH) pathway that plays an important role in development, maintenance, and regeneration of almost all adult tissues. Recombinant human DCuN1D1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

DCN1-like protein 1, DCuN1L1, RP42, SCCRO, SCRO, Tes3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

32.2 kDa (279aa) confirmed by MALDI-TOF

Additionnal Information

DCUN1D1, DCN1-like protein 1, DCuN1L1, RP42, SCCRO, SCRO, Tes3, ATGP0884-10 µg, ATGP0884-20 µg, ATGP0884-50 µg, ATGP0884-100 µg, ATGP0884-250 µg, ATGP0884-500 µg, ATGP0884-1 mg, ATGP0884-10, ATGP0884-20, ATGP0884-50, ATGP0884-100, ATGP0884-250, ATGP0884-500, ATGP0884-1

References & Citations

Estilo C.L., et al. (2003) . Clin. Cancer Res, 9: 2300-2306.; ; Lum L., et al. (2004) . Science., 304: 1755-1759.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Scientific Category

Cancer

NCBI Accession Number

NP_065691

Uniprot Accession Number

Q96GG9

Species

Human

AA Sequence

MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI DDFVEFARPQ IAGTKSTTV