Recombinant human DCUN1D1 protein
DCuN1D1, also known as DCN1-like protein 1, is involved in the malignant transformation of squamous cell lineage. This protein regulates Gli1, a key regulator of the hedgehog (HH) pathway that plays an important role in development, maintenance, and regeneration of almost all adult tissues. Recombinant human DCuN1D1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
DCN1-like protein 1, DCuN1L1, RP42, SCCRO, SCRO, Tes3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
32.2 kDa (279aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Estilo C.L., et al. (2003) . Clin. Cancer Res, 9: 2300-2306.; ; Lum L., et al. (2004) . Science., 304: 1755-1759.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_065691
Uniprot Accession Number
Q96GG9
Species
Human
AA Sequence
Frequently Asked Questions
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