Recombinant human TPM2 protein
Tropomyosin beta chain isoform 2, also known as TPM2, is a member of the actin filament binding protein family which mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Recombinant human TPM2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Tropomyosin beta chain isoform 2, AMCD1, DA1, DA2B, NEM4, TMSB
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
35.1 kDa (304aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Hunt CC., et al. (1995) Cytogenet Cell Genet. 71 (1) :94-5.; ; Tiso N., et al. (1997) Biochem Biophys Res Commun. 13 (2) :347-50.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 100 mM NaCl
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_998839.1
Uniprot Accession Number
P07951
Species
Human
AA Sequence
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