Recombinant human MOBKL1B/MOB1A protein

MOBKL1B, also known as MOB1B, belongs to the MOB1/phocein family. It stimulates the kinase activity of STK38 and STK38L. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase. Therefore, MOBKL1B participates in cell cycle checkpoint control and tumor inhibition. Recombinant human MOBKL1B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

MOB kinase activator 1A, Mob1 alpha, Mob1A, Mob1 homolog 1B, Mps one binder kinase activator-like 1B, MOB1 Mps One Binder homolog A, MOB4B, MOBK1B, MOBKL1B

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

27.2 kDa (236aa) confirmed by MALDI-TOF

Additionnal Information

Mps one binder kinase activator-like 1B, MOBKL1B, MOBK1B, MOB4B, Mob1A, MOB1 Mps One Binder homolog A, Mob1 homolog 1B, Mob1 alpha, Mob1 A, MOB1, MOB kinase activator 1A, MATS1, FLJ11595, FLJ10788, C2orf6, ATGP0866-10 µg, ATGP0866-20 µg, ATGP0866-50 µg, ATGP0866-100 µg, ATGP0866-250 µg, ATGP0866-500 µg, ATGP0866-1 mg, ATGP0866-010, ATGP0866-020, ATGP0866-050, ATGP0866-100, ATGP0866-250, ATGP0866-500, ATGP0866-01M

References & Citations

Lai ZC., et al. (2005) Cell. 120 (5) :675-85.; ; Bichsel SJ., et al. (2004) J Biol Chem. 279 (34) :35228-35.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 30% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_060691

Uniprot Accession Number

Q9H8S9

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MSFLFSSRSS KTFKPKKNIP EGSHQYELLK HAEATLGSGN LRQAVMLPEG EDLNEWIAVN TVDFFNQINM LYGTITEFCT EASCPVMSAG PRYEYHWADG TNIKKPIKCS APKYIDYLMT WVQDQLDDET LFPSKIGVPF PKNFMSVAKT ILKRLFRVYA HIYHQHFDSV MQLQEEAHLN TSFKHFIFFV QEFNLIDRRE LAPLQELIEK LGSKDR