Recombinant human RAB27B protein

RAB27B belongs to the RAB family and is a critical regulator of vesicular transport. This protein is expressed in pituitary tissue, but is more significantly expressed in brain and spleen. RAB27B may be functionally redundant to Rab27a, as it can rescue Rab27a mutants. Recombinant human RAB27B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ras-related protein Rab-27B, Ras-related protein Rab-27B, C25KG, RAB27B member RAS oncogene family

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26.7 kDa (238aa) confirmed by MALDI-TOF

Additionnal Information

RAB27B, Ras-related protein Rab-27B, Ras-related protein Rab-27B, C25KG, ATGP0863-10 µg, ATGP0863-20 µg, ATGP0863-50 µg, ATGP0863-100 µg, ATGP0863-250 µg, ATGP0863-500 µg, ATGP0863-1 mg, ATGP0863-10, ATGP0863-20, ATGP0863-50, ATGP0863-100, ATGP0863-250, ATGP0863-500, ATGP0863-1

References & Citations

Ostrowski M., et al. (2010) Nat Cell Biol. 12 (1) :19-30.; ; Song J., et al. (2009) Proc Natl Acad Sci u S A. 106 (35) :14966-71.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_004154

Uniprot Accession Number

O00194

Species

Human

AA Sequence

MTDGDYDYLI KLLALGDSGV GKTTFLYRYT DNKFNPKFIT TVGIDFREKR VVYNAQGPNG SSGKAFKVHL QLWDTAGQER FRSLTTAFFR DAMGFLLMFD LTSQQSFLNV RNWMSQLQAN AYCENPDIVL IGNKADLPDQ REVNERQARE LADKYGIPYF ETSAATGQNV EKAVETLLDL IMKRMEQCVE KTQIPDTVNG GNSGNLDGEK PPEKKCIC