Recombinant human EMAP-II protein
AIMP1, also known as EMPA2 or p43, is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Recombinant human AIMP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by BCA assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
39.2 kDa (356aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Zhu X., et al. (2009) Proc Natl Acad Sci u S A. 106 (37) :15944-9.; ; Kim E., et al. (2008) J Immunol. 180 (5) :2894-902.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 2mM DTT, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_001135888
Uniprot Accession Number
Q12904
Species
Human
AA Sequence
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