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Recombinant human EMAP-II protein

AIMP1, also known as EMPA2 or p43, is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Recombinant human AIMP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP2, EMAPII, p43, SCYE1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by BCA assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

39.2 kDa (356aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

EMAP-2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP2, EMAPII, p43, SCYE1, ATGP0852-10 µg, ATGP0852-20 µg, ATGP0852-50 µg, ATGP0852-100 µg, ATGP0852-250 µg, ATGP0852-500 µg, ATGP0852-1 mg, ATGP0852-10, ATGP0852-20, ATGP0852-50, ATGP0852-100, ATGP0852-250, ATGP0852-500, ATGP0852-1

References & Citations

Zhu X., et al. (2009) Proc Natl Acad Sci u S A. 106 (37) :15944-9.; ; Kim E., et al. (2008) J Immunol. 180 (5) :2894-902.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 2mM DTT, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_001135888

Uniprot Accession Number

Q12904

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MLPAVAVSEP VVLRFMIFCR LLAKMANNDA VLKRLEQKGA EADQIIEYLK QQVSLLKEKA ILQATLREEK KLRVENAKLK KEIEELKQEL IQAEIQNGVK QIPFPSGTPL HANSMVSENV IQSTAVTTVS SGTKEQIKGG TGDEKKAKEK IEKKGEKKEK KQQSIAGSAD SKPIDVSRLD LRIGCIITAR KHPDADSLYV EEVDVGEIAP RTVVSGLVNH VPLEQMQNRM VILLCNLKPA KMRGVLSQAM VMCASSPEKI EILAPPNGSV PGDRITFDAF PGEPDKELNP KKKIWEQIQP DLHTNDECVA TYKGVPFEVK GKGVCRAQTM SNSGIK

Frequently Asked Questions

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