Recombinant human RAC3 protein

RAC3 is a member of the Rac subfamily of the Rho small G proteins. This protein is a small (~21 kDa) monomeric GTP-binding protein, and is an important component of intracellular signalling pathway, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Recombinant human RAC3 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ras-related C3 botulinum toxin substrate 3, p21-Rac3, Rac1B, RAS related C3 botulinum substrate 3, Ras related C3 botulinum toxin substrate 3, rho family small GTP binding protein Rac3, Rho family small GTP binding protein Rac3, RP23-84C12.18

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

21 kDa (189aa) confirmed by MALDI-TOF

Additionnal Information

RAC3, ras-related C3 botulinum toxin substrate 3, p21-Rac3, Rac1B, RAS related C3 botulinum substrate 3, Ras related C3 botulinum toxin substrate 3, rho family small GTP binding protein Rac3, Rho family small GTP binding protein Rac3, RP23-84C12.18, ATGP0843-10 µg, ATGP0843-20 µg, ATGP0843-50 µg, ATGP0843-100 µg, ATGP0843-250 µg, ATGP0843-500 µg, ATGP0843-1 mg, ATGP0843-10, ATGP0843-20, ATGP0843-50, ATGP0843-100, ATGP0843-250, ATGP0843-500, ATGP0843-1

References & Citations

De Langhe S., et al. (2002) Int. J. Mol. Med. 9:451-459; ; Haataja L, et al. (1997) J. Biol. Chem. 272 (33) : 20384-88.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 200 mM NaCl, 0.1mM PMSF, 1mM EDTA

Scientific Category

Signal Transduction

NCBI Accession Number

NP_005043

Uniprot Accession Number

P60763

Species

Human

AA Sequence

MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPHTPI LLVGTKLDLR DDKDTIERLR DKKLAPITYP QGLAMAREIG SVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKPGKKC