Recombinant human ISCU protein

Iron-sulfur cluster assembly enzyme, also known as ISCu, is a member of the nifu family. Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. It is interact with ISCS, a cysteine desulfurase, to sequester inorganic sulfur for Fe-S cluster assembly. ISCu-ISCS protein complex localizes in both mitochondria and cytosol, implying that Fe-S cluster assembly takes place in multiple subcellular compartments in mammalian cells. Recombinant human ISCu protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Iron-sulfur cluster assembly enzyme, NIFUN, NifU-like N-terminal domain containing protein, NifU-like protein, IscU iron-sulfur cluster scaffold homolog, iron-sulfur cluster scaffold homolog, ISU2, hnifU

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

16.7 kDa (154aa) confirmed by MALDI-TOF

Additionnal Information

ISCu, Iron-sulfur cluster assembly enzyme ISCu, HML, hnifu, ISu2, NIFu, NIFuN, ATGP0842-10 µg, ATGP0842-20 µg, ATGP0842-50 µg, ATGP0842-100 µg, ATGP0842-250 µg, ATGP0842-500 µg, ATGP0842-1 mg, ATGP0842-10, ATGP0842-20, ATGP0842-50, ATGP0842-100, ATGP0842-250, ATGP0842-500, ATGP0842-1