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Recombinant human IGF-2 protein

IGF2, as known as insulin-like growth factor 2, is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. This protein is a fetal growth factor, influenced by placental lactogen and abundantly expressed by placental trophoblasts. Recombinant human IGF2 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Product Specifications

Product Name Alternative

Insulin-like growth factor 2, Somatomedin-A, INSIGF, Preptin, Insulin-like growth factor II, IGF-II, T3M-11-derived growth factor

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

7.6 kDa (68aa) confirmed by MALDI-TOF

Additionnal Information

IGF-2, Insulin-like growth factor 2, Somatomedin-A, INSIGF, ATGP0836-10 µg, ATGP0836-20 µg, ATGP0836-50 µg, ATGP0836-100 µg, ATGP0836-250 µg, ATGP0836-500 µg, ATGP0836-1 mg, ATGP0836-10, ATGP0836-20, ATGP0836-50, ATGP0836-100, ATGP0836-250, ATGP0836-500, ATGP0836-1

References & Citations

Bell G.I., et al. (1984), Nature 310: 775-777; ; Pedersen S.K., et al. (2002) . Biochem. J. 363: 37-44.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. phosphate-buffered saline (pH 7.4) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_000603

Uniprot Accession Number

P01344

Species

Human

AA Sequence

MAYRPSETLC GGELVDTLQF VCGDRGFYFS RPASRVSRRS RGIVEECCFR SCDLALLETY CATPAKSE

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