Recombinant human ROBLD3/LAMTOR2 protein
ROBLD3, also known as MAPBPIP, belongs to the GAMAD family. It is an adapter protein that enhances the efficiency of the MAP kinase cascade and facilitates the activation of MAPK2. ROBLD3 compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes. Recombinant human ROBLD3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA)
Purity
> 95% by SDS-PAGE
Molecular Weight
16 kDa (149aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sancak Y., et al. (2010) Cell. 141 (2) :290-303.; ; Waters S., et al. (2009) FEBS Lett. 583 (12) :1846-52.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_054736.1
Uniprot Accession Number
Q9Y2Q5
Species
Human
AA Sequence
MLRPKA LTQVLSQANT GGVQSTLLLN NEGSLLAYSG YGDTDARVTA AIASNIWAAY DRNGNQAFNE DNLKFILMDC MEGRVAITRV ANLLLCMYAK ETVGFGMLKA KAQALVQYLE EPLTQVAAS
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items