Recombinant human GRP78/HSPA5 protein

Binding immunoglobulin protein (BiP) belongs to the family of ~70 kDa heat shock proteins (HSP 70) . It is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis. Recombinant human BIP protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Heat shock protein family A member 5, Heat shock 70kD protein 5, HSP70 family protein 5, Glucose-regulated protein 78kD, Binding-immunoglobulin protein, BiP, Endoplasmic reticulum chaperone BiP, Glucose-regulated protein 78kDa, Immunoglobulin heavy chain-binding protein

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

71 kDa (640aa)

Additionnal Information

GRP78, HSPA5, Binding immunoglobulin protein, HSPA5, heat shock 70kDa protein 5, GRP78, glucose-regulated protein 78kD, MIF2, ATGP0824-10 µg, ATGP0824-20 µg, ATGP0824-50 µg, ATGP0824-100 µg, ATGP0824-250 µg, ATGP0824-500 µg, ATGP0824-1 mg, ATGP0824-10, ATGP0824-20, ATGP0824-50, ATGP0824-100, ATGP0824-250, ATGP0824-500, ATGP0824-1