Recombinant human RGS19 protein

RGS19, also known as Regulator of G-protein signaling 19, belongs to RGS (regulator of G protein signaling) family and negatively regulates G protein coupled receptor signaling. This protein specifically interacts with heterotrimeric GTP-binding protein G alpha i3 (GAI3) . Recombinant human RGS19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Regulator of G-protein signaling 19, GAIP, GNAI3IP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26.7 kDa (237aa) confirmed by MALDI-TOF

Additionnal Information

RGS19, Regulator of G-protein signaling 19, GAIP, GNAI3IP, ATGP0810-10 µg, ATGP0810-20 µg, ATGP0810-50 µg, ATGP0810-100 µg, ATGP0810-250 µg, ATGP0810-500 µg, ATGP0810-1 mg, ATGP0810-10, ATGP0810-20, ATGP0810-50, ATGP0810-100, ATGP0810-250, ATGP0810-500, ATGP0810-1

References & Citations

Wong YH., et al. (2010) Cell Signal. 22 (11) :1700-7.; ; Farquhar MG., et al (1995) Proc Natl Acad Sci u S A. 92 (25) :11916-20.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_001034556

Uniprot Accession Number

P49795

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MPTPHEAEKQ ITGPEEADRP PSMSSHDTAS PAAPSRNPCC LCWCCCCSCS WNQERRRAWQ ASRESKLQPL PSCEVCATPS PEEVQSWAQS FDKLMHSPAG RSVFRAFLRT EYSEENMLFW LACEELKAEA NQHVVDEKAR LIYEDYVSIL SPKEVSLDSR VREGINKKMQ EPSAHTFDDA QLQIYTLMHR DSYPRFLSSP TYRALLLQGP SQSSSEA