Recombinant human SDCBP protein
SDCBP, also known as Syntenin1, is a multifunctional intracellular adapter protein. This protein contains tandemly repeated PDZ domains that react with the FYA (phe-tyr-ala) carboxyterminal amino acid sequence of the syndecans. It is involved in organization of protein complexes in the plasma membranes, regulation of B-cell development, activation of transcription factors, intracellular trafficking and cell-surface targeting, synaptic transmission, and axonal outgrowth. Recombinant human SDCBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Syntenin-1, MDA-9, ST1, SYCL, TACIP18
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
34.6 kDa (318aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Lee CH., et al. (2010) Comp Biochem Physiol C Toxicol Pharmacol. 152 (2) :195-201.; ; Fisher PB., et al (2008) Cancer Res. 68 (9) :3087-93.
Other References
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl, 40% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_005616.2
Uniprot Accession Number
O00560
Species
Human
AA Sequence
Frequently Asked Questions
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