Recombinant human MP1/LAMTOR3 protein
MAPKSP1 (Mitogen-activated protein kinase scaffold protein 1) is a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Recombinant human MAPKSP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Mitogen-activated protein kinase scaffold protein 1, MAP2K1IP1, MAPBP, MP1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
15.8 kDa (144aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wunderlich, et al. (2001) J. Cell Biol. (united States) 152 (4) : 765-76.; ; Schaeffer HJ, et al. (1998) Science 281 (5383) : 1668-71.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 5mM DTT, 100 mM NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_068805
Uniprot Accession Number
Q9UHA4
Species
Human
AA Sequence
Frequently Asked Questions
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