Recombinant human Uridine-cytidine kinase 2/UCK2 protein
UCK2 also known as uridine-cytidine kinase 2 is belongs to the uridinekinase family. uCK2 catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate and cytidine monophosphate. It plays a role in the production of pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B. Recombinant human uCK2 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Uridine-cytidine kinase 2, Uridine monophosphokinase 2, uMPK, uK, TSA903, Testis-specific protein, MOX2 receptor, Cytidine monophosphokinase 2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
30.3 kDa (269aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Smith AJ., et al. (2009) Org Biomol Chem. 7 (13) :2716-24.; ; Murata D., et al (2004) Drug Metab Dispos. 32 (10) :1178-82
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 100 mM NaCl, 0.1mM PMSF, 1mM EDTA
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_036606.2
Uniprot Accession Number
Q9BZX2
Species
Human
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