Recombinant human TCP1 protein
TCP1 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This protein is found in the cytosol as a subunit of a hetero-oligomeric chaperone. It has an important function in maintaining cellular homoeostasis by assisting the folding of many proteins, including the cytoskeletal components actin and tubulin. Recombinant human TCP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
T-complex protein 1 subunit alpha, CCT-alpha, CCT1, CCT, TCP-1-alpha
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
62.5 kDa (576aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Willison KR., et al. (2008) EMBO J. 27 (13) :1827-39; ; Kubota H., et al (2001) Eur J Biochem. 268 (17) :4664-73.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1mM PMSF,10% glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_110379
Uniprot Accession Number
P17987
Species
Human
AA Sequence
Frequently Asked Questions
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