Recombinant human BART1/ARL2BP protein

ARL2BP is an effector of ADP-ribosylation factor-like 2 (ARL2) that is essential for nuclear retention of STAT3. This protein binds to ARL2. GTP with high affinity but does not interact with ARL2. GDP, activated ARF, or RHO proteins. Though predominantly cytosolic, ARL2BP can enter the mitochondria and bind the adenine nucleotide transporter when bound to ARL2. Thus it may also be involved in mitochondria transport and apoptosis. Recombinant human ARL2BP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

ADP-ribosylation factor-like 2 binding protein, BART, BART1, ADP ribosylation factor like GTPase 2 binding protein, ARF-like 2-binding protein, ARL2-binding protein, Retinitis pigmentosa 66, Binder of Arl2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

20.9 kDa (183aa) confirmed by MALDI-TOF

Additionnal Information

ARL2BP, ADP-ribosylation factor-like 2 binding protein, BART, BART1, ATGP0765-10 µg, ATGP0765-20 µg, ATGP0765-50 µg, ATGP0765-100 µg, ATGP0765-250 µg, ATGP0765-500 µg, ATGP0765-1 mg, ATGP0765-10, ATGP0765-20, ATGP0765-50, ATGP0765-100, ATGP0765-250, ATGP0765-500, ATGP0765-1

References & Citations

Ding J., et al (2009) Structure. 17 (4) :602-10.; ; Kahn RA., et al. (1999) J Biol Chem. 274 (39) :27553-61.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_036238

Uniprot Accession Number

Q9Y2Y0

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH