Recombinant human CARHSP1 protein

CRAHSP1 is a serine phosphoprotein originally identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B) . This protein interacts with the STYX/dead phosphate protein in developing spermatids and is a paralog of the brain-specific mRNA-binding protein PIPPIN. It is thought to play a common role in calcium-mediated signal transduction resulting from phosphorylation on serine residues. Recombinant human CRAHSP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Calcium-regulated heat stable protein 1, CRHSP-24, CSDC1, MGC111446, Calcium-regulated heat stable protein 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by BCA assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

18 kDa (167aa) confirmed by MALDI-TOF

Additionnal Information

CARHSP1, Calcium-regulated heat stable protein 1, CRHSP-24, CSDC1, MGC111446, Calcium-regulated heat stable protein 1, ATGP0729-10 µg, ATGP0729-20 µg, ATGP0729-50 µg, ATGP0729-100 µg, ATGP0729-250 µg, ATGP0729-500 µg, ATGP0729-1 mg, ATGP0729-10, ATGP0729-20, ATGP0729-50, ATGP0729-100, ATGP0729-250, ATGP0729-500, ATGP0729-1

References & Citations

Schafer C., et al. (2003) Am J Physiol Gastrointest Liver Physiol.. 285:G726-34; ; Groblewski G.E, et al. (1998) J. Biol. Chem. 273: 22738-22744.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_055131

Uniprot Accession Number

Q9Y2V2

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MSSEPPPPPQ PPTHQASVGL LDTPRSRERS PSPLRGNVVP SPLPTRRTRT FSATVRASQG PVYKGVCKCF CRSKGHGFIT PADGGPDIFL HISDVEGEYV PVEGDEVTYK MCSIPPKNEK LQAVEVVITH LAPGTKHETW SGHVISS