Recombinant human CARHSP1 protein
CRAHSP1 is a serine phosphoprotein originally identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B) . This protein interacts with the STYX/dead phosphate protein in developing spermatids and is a paralog of the brain-specific mRNA-binding protein PIPPIN. It is thought to play a common role in calcium-mediated signal transduction resulting from phosphorylation on serine residues. Recombinant human CRAHSP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Specifications
Product Name Alternative
Calcium-regulated heat stable protein 1, CRHSP-24, CSDC1, MGC111446, Calcium-regulated heat stable protein 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
18 kDa (167aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Schafer C., et al. (2003) Am J Physiol Gastrointest Liver Physiol.. 285:G726-34; ; Groblewski G.E, et al. (1998) J. Biol. Chem. 273: 22738-22744.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_055131
Uniprot Accession Number
Q9Y2V2
Species
Human
AA Sequence
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