Recombinant human SEPT2/SEPTIN2 protein

Septin2 (SEPT2) is a GTPase that is required for cytokinesis and associated with exocytosis. This protein can hetero-oligomerize with Septin6, 7 and also plays a role in the organization of new growth in organisms. It is associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Recombinant human Septin2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Septin 2, hNedd5, KIAA0158, DIFF6, Pnutl3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

43.6 kDa (381aa) confirmed by MALDI-TOF

Additionnal Information

SETP 2, SETP-2, Septin-2, Septin 2, hNedd5, KIAA0158, DIFF6, Pnutl3, ATGP0717-10 µg, ATGP0717-20 µg, ATGP0717-50 µg, ATGP0717-100 µg, ATGP0717-250 µg, ATGP0717-500 µg, ATGP0717-1 mg, ATGP0717-010, ATGP0717-020, ATGP0717-050, ATGP0717-100, ATGP0717-250, ATGP0717-500, ATGP0717-01M

References & Citations

Low C, et al.. (2006) J Biol Chem. 281 (41) :30697-706.; ; Kremer BE, et al. (2007) Cell. 130 (5) :837-50.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Cell Cycle

NCBI Accession Number

AAH14455

Uniprot Accession Number

Q15019

Species

Human

AA Sequence

MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK STLINSLFLT DLYPERVISG AAEKIERTVQ IEASTVEIEE RGVKLRLTVV DTPGYGDAIN CRDCFKTIIS YIDEQFERYL HDESGLNRRH IIDNRVHCCF YFISPFGHGL KPLDVAFMKA IHNKVNIVPV IAKADTLTLK ERERLKKRIL DEIEEHNIKI YHLPDAESDE DEDFKEQTRL LKASIPFSVV GSNQLIEAKG KKVRGRLYPW GVVEVENPEH NDFLKLRTML ITHMQDLQEV TQDLHYENFR SERLKRGGRK VENEDMNKDQ ILLEKEAELR RMQEMIARMQ AQMQMQMQGG DGDGGALGHH V