Recombinant human ADAT2 protein
Adenosine deaminase (ADA), also known as ADAT2 is an enzyme involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Also, ADAT2 is thought to participate in the deamination of adenosine-34 to inosine in many tRNAs. Belonging to the cytidine and deoxycytidylate deaminase protein family, ADAT2 employs zinc as a cofactor. ADAT2 is a 191 amino acid protein that exists as two isoforms produced by alternative splicing events. Recombinant human ADAT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
TRNA-specific adenosine deaminase 2, DEADC1, TAD2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.2 kDa (211aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Persico AM, et al. (2000) Am. J. Med. Genet. 96 (6) : 784-90.; ; Kimura, K., et al. (2006) Genome Res. 16: 55-65.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 50 mM NaCl
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_872309
Uniprot Accession Number
Q7Z6V5
Species
Human
AA Sequence
Frequently Asked Questions
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