Recombinant human GGPS1 protein
Geranylgeranyl pyrophosphate synthase isoform A, also known as GGPS1, is a member of the prenyltransferase family. Predominantly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate, a precursor of geranylgeranylated proteins and carotenoids. GGPS1 is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Recombinant human GGPS1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Geranylgeranyl pyrophosphate synthase isoform A, Geranylgeranyl pyrophosphate synthase isoform A, GGPPS, GGPPS1, GGPP synthetase
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
37 kDa (320aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Okada K., et al. (2000) Plant Physiol. 122:1045-1056.; ; Kainou T., et al. (1999) Biochem Biophys. 1437:330-340.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_001032354
Uniprot Accession Number
O95749
Species
Human
AA Sequence
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