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Recombinant human CCL13/MCP-4 protein

CCL13 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC) . This protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. It can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha. Recombinant human CCL13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

C-C motif chemokine 13, CK-beta-10, Monocyte chemoattractant protein 4, Monocyte chemotactic protein 4, MCP-4, NCC-1, Small-inducible cytokine A13, MCP4, NCC1, SCYA13, SCYL1, CKb10

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by BCA assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

10.8 kDa (96aa) confirmed by MALDI-TOF

Additionnal Information

CCL13, MCP4, C-C motif chemokine 13, CKb10, MCP-4, NCC-1, NCC1, SCYA1, SCYL1, CK-beta-10, Small-inducible cytokine A13, C-C motif chemokine 13, MCP4, C-C motif chemokine 13, chemokine (C-C motif) ligand 13, ckbeta10, ATGP0696-10 µg, ATGP0696-20 µg, ATGP0696-50 µg, ATGP0696-100 µg, ATGP0696-250 µg, ATGP0696-500 µg, ATGP0696-1 mg, ATGP0696-10, ATGP0696-20, ATGP0696-50, ATGP0696-100, ATGP0696-250, ATGP0696-500, ATGP0696-1

References & Citations

Garcia-Zepeda EA, et al.. (1996) J Immunol. 157:5613-5626

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_005399

Uniprot Accession Number

Q99616

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK AHTLKT

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