Recombinant human TES protein

TES is a tumor suppressor protein and may play role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. This protein localizes to cell-cell contacts and actin stress fibres, and interacts with a variety of cytoskeletal proteins including Zyxin, Mena, VASP, Talin and Actin. The ability of TES to associate with alpha-actinin, paxillin and Zyxin is dependent on the conformational state of the molecule. Recombinant human TES protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Testin, TESS, TESS-2, Testin

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

50.1 kDa (441aa) confirmed by MALDI-TOF

Additionnal Information

TES, Testin, TESS, TESS-2, Testin, ATGP0684-10 µg, ATGP0684-20 µg, ATGP0684-50 µg, ATGP0684-100 µg, ATGP0684-250 µg, ATGP0684-500 µg, ATGP0684-1 mg, ATGP0684-10, ATGP0684-20, ATGP0684-50, ATGP0684-100, ATGP0684-250, ATGP0684-500, ATGP0684-1

References & Citations

Qiu H., et al. (2010) Cancer Sci. 101 (5) :1255-60.; ; Sato T., et al. (2003) J Biol Chem. 278 (48) :47534-44.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_056456

Uniprot Accession Number

Q9UGI8

Species

Human

AA Sequence

MDLENKVKKM GLGHEQGFGA PCLKCKEKCE GFELHFWRKI CRNCKCGQEE HDVLLSNEED RKVGKLFEDT KYTTLIAKLK SDGIPMYKRN VMILTNPVAA KKNVSINTVT YEWAPPVQNQ ALARQYMQML PKEKQPVAGS EGAQYRKKQL AKQLPAHDQD PSKCHELSPR EVKEMEQFVK KYKSEALGVG DVKLPCEMDA QGPKQMNIPG GDRSTPAAVG AMEDKSAEHK RTQYSCYCCK LSMKEGDPAI YAERAGYDKL WHPACFVCST CHELLVDMIY FWKNEKLYCG RHYCDSEKPR CAGCDELIFS NEYTQAENQN WHLKHFCCFD CDSILAGEIY VMVNDKPVCK PCYVKNHAVV CQGCHNAIDP EVQRVTYNNF SWHASTECFL CSCCSKCLIG QKFMPVEGMV FCSVECKKRM S