Recombinant human Galectin-2/LGALS2 protein
LGALS2, also known as galectin2, is a soluble beta-galactoside binding lectin that modulates cell-to-cell adhesion and cell-to-extracellular matrix interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. This protein induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-alpha (LTA) with possible implications in risk of myocardial infarction. Recombinant human Galectin 2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Galectin2, HL14, Gal-2, Beta-galactoside-binding lectin L-14-II, Lactose-binding lectin 2, S-Lac lectin 2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
16.8 kDa (152aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Loser K., et al. (2009) J Immunol. 182 (9) :5419-29.; ; Ozaki K., et al. (2009) Nat Genet. 41 (3) :329-33.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_006489
Uniprot Accession Number
P05162
Species
Human
AA Sequence
MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG ELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE
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