Recombinant human Galectin-2/LGALS2 protein
LGALS2, also known as galectin2, is a soluble beta-galactoside binding lectin that modulates cell-to-cell adhesion and cell-to-extracellular matrix interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. This protein induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-alpha (LTA) with possible implications in risk of myocardial infarction. Recombinant human Galectin 2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Galectin2, HL14, Gal-2, Beta-galactoside-binding lectin L-14-II, Lactose-binding lectin 2, S-Lac lectin 2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
16.8 kDa (152aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Loser K., et al. (2009) J Immunol. 182 (9) :5419-29.; ; Ozaki K., et al. (2009) Nat Genet. 41 (3) :329-33.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_006489
Uniprot Accession Number
P05162
Species
Human
AA Sequence
MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG ELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Lentiviral human BARX2 shRNA (UAS) - Lentiviral human BARX2 shRNA (UAS, iRFP) plasmid
OriCell™ Complete Medium For Human Umbilical Artery Smooth Muscle Cells