Recombinant human ERP44 protein
ERP44 is a novel endoplasmic reticulum chaperone involved in thiol-dependent retention of the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. The protein inhibits the calcium channel activity of ITPR1. This protein may have a role in the control of oxidative protein folding in the endoplasmic reticulum. Recombinant human ERP44 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Endoplasmic reticulum protein 44, PDIA10, TXNDC4, ER protein 44, Endoplasmic reticulum protein 44
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
48.0 kDa (415aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Von Figura K., et al. (2008) J Biol Chem. 283 (10) :6375-83.; ; Sitia R., et al. (2002) EMBO J. 21 (4) :835-44;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_055866
Uniprot Accession Number
Q9BS26
Species
Human
AA Sequence
Frequently Asked Questions
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