Recombinant human ERP44 protein

ERP44 is a novel endoplasmic reticulum chaperone involved in thiol-dependent retention of the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. The protein inhibits the calcium channel activity of ITPR1. This protein may have a role in the control of oxidative protein folding in the endoplasmic reticulum. Recombinant human ERP44 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Endoplasmic reticulum protein 44, PDIA10, TXNDC4, ER protein 44, Endoplasmic reticulum protein 44

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

48.0 kDa (415aa) confirmed by MALDI-TOF

Additionnal Information

ERP44, Endoplasmic reticulum protein 44, PDIA10, TXNDC4, ER protein 44, Endoplasmic reticulum protein 44, ATGP0678-10 µg, ATGP0678-20 µg, ATGP0678-50 µg, ATGP0678-100 µg, ATGP0678-250 µg, ATGP0678-500 µg, ATGP0678-1 mg, ATGP0678-10, ATGP0678-20, ATGP0678-50, ATGP0678-100, ATGP0678-250, ATGP0678-500, ATGP0678-1

References & Citations

Von Figura K., et al. (2008) J Biol Chem. 283 (10) :6375-83.; ; Sitia R., et al. (2002) EMBO J. 21 (4) :835-44;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol

Scientific Category

Heat Shock Proteins

NCBI Accession Number

NP_055866

Uniprot Accession Number

Q9BS26

Species

Human

AA Sequence

EI TSLDTENIDE ILNNADVALV NFYADWCRFS QMLHPIFEEA SDVIKEEFPN ENQVVFARVD CDQHSDIAQR YRISKYPTLK LFRNGMMMKR EYRGQRSVKA LADYIRQQKS DPIQEIRDLA EITTLDRSKR NIIGYFEQKD SDNYRVFERV ANILHDDCAF LSAFGDVSKP ERYSGDNIIY KPPGHSAPDM VYLGAMTNFD VTYNWIQDKC VPLVREITFE NGEELTEEGL PFLILFHMKE DTESLEIFQN EVARQLISEK GTINFLHADC DKFRHPLLHI QKTPADCPVI AIDSFRHMYV FGDFKDVLIP GKLKQFVFDL HSGKLHREFH HGPDPTDTAP GEQAQDVASS PPESSFQKLA PSEYRYTLLR DRDEL