Recombinant human TALDO1 protein
TALDO1 is a key enzyme of the non-oxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This protein transfers a dihydroxyacetone group from donor compounds (fructose 6-phosphate or sedoheptulose 7-phosphate) to aldehyde acceptor compounds. It is expressed at selectively high levels in oligodendrocytes of the brain. Deficiency of TALDO1 causes accumulation of erythritol, D-arabitol, and ribitol. Recombinant human TALDO1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Transaldolase 1, TAL, TAL-H, TALDOR, TALH, TALDO1, Transaldolase 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
39.7 kDa (357aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sprenger GA., et al. (2009) Int J Biochem Cell Biol. 41 (7) :1482-94.; ; Saudubray JM., et al (2006) J Pediatr. 149 (5) :713-7.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_006746
Uniprot Accession Number
P37837
Species
Human
AA Sequence
Frequently Asked Questions
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