Recombinant human PDAP1 protein
PDGFA associated protein 1, also known as PDAP1, enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. And its expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha. Recombinant human PDAP1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
PDGFA associated protein 1, HASPP28, PAP, PAP1, PDGFA associated protein 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
21.6 kDa (189aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zahedi R.P., et al. (2008) J. Proteome Res. 7:526-534; ; Malka D., et al. (2000) Gastroenterology. 119 (3) :816-28.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 100 mM NaCl, 0.1mM PMSF
Scientific Category
Signal Transduction
NCBI Accession Number
NP_055706
Uniprot Accession Number
Q13442
Species
Human
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