Recombinant human p47phox/NCF1 protein

Neutrophil cytosolic factor 1, also known as NCF1, is a cytosolic subunit of neutrophil NADPH oxidase. NCF1, along with NCF2 and a membrane bound cytochrome b558, is required for activation of the latent NADPH oxidase necessary for superoxide production. Defects in NCF1, often resulting from recombination between NCF1 and a nearby homologous pseudogene, cause chronic granulomatous disease. Recombinant human NCF1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Neutrophil cytosol factor 1, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox-organizing protein 2, SH3 and PX domain-containing protein 1A, NADPH oxidase organizer 2, NOXO2, SH3PXD1A, NCF1A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

45.7 kDa (398aa) confirmed by MALDI-TOF

Additionnal Information

SH3PXD1A, SH3 and PX domain-containing protein 1A, SH3 and PX domain containing protein 1A, p47phox, Nox-organizing protein 2, NOXO2, Nox organizing protein2, Nox organizing protein 2, Nox organizer 2, Neutrophil NADPH oxidase factor 1, Neutrophil cytosol factor 1, NCF-47K, NCF47K, NCF1A, NCF1, NCF 47K, NADPH oxidase organizer 2, 47kDa neutrophil oxidase factor, 47kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, 47 kDa autosomal chronic granulomatous disease protein, ATGP0653-10 µg, ATGP0653-20 µg, ATGP0653-50 µg, ATGP0653-100 µg, ATGP0653-250 µg, ATGP0653-500 µg, ATGP0653-1 mg, ATGP0653-010, ATGP0653-020, ATGP0653-050, ATGP0653-100, ATGP0653-250, ATGP0653-500, ATGP0653-01M