Recombinant human Glutathione S-transferase mu 4/GSTM4 protein

Glutathione S-transferase Mu 4 isoform 1, also known as GSTM4, is member of the glutathione s-transferase (GST) family of proteins. There are eight families of GST proteins, namely alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have a variety of functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. Recombinant human GSTM4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Glutathione S-transferase Mu 4 isoform 1, GSTM4-4, GTM4, GST class-mu 4, GST-Mu2, Glutathione S-transferase Mu 4 isoform 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

27.7 kDa (238aa) confirmed by MALDI-TOF

Additionnal Information

Glutathione S-transferase Mu4, GSTM4, Glutathione S-transferase Mu 4 isoform 1, GSTM4-4, GTM4, GST class-mu 4, GST-Mu2, Glutathione S-transferase Mu 4 isoform 1, ATGP0649-10 µg, ATGP0649-20 µg, ATGP0649-50 µg, ATGP0649-100 µg, ATGP0649-250 µg, ATGP0649-500 µg, ATGP0649-1 mg, ATGP0649-10, ATGP0649-20, ATGP0649-50, ATGP0649-100, ATGP0649-250, ATGP0649-500, ATGP0649-1

References & Citations

Boqaards JJ., et al. (1992) Biochem J. 289 (2) :383-8.; ; Rozell B., et al. (1992) Xenobiotica. 23 (8) :835-49.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 50 mM NaCl

Scientific Category

Enzymes & Proteases

NCBI Accession Number

NP_000841

Uniprot Accession Number

Q03013

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MSMTLGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQAMDVSNQ LARVCYSPDF EKLKPEYLEE LPTMMQHFSQ FLGKRPWFVG DKITFVDFLA YDVLDLHRIF EPNCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPKPLYT RVAVWGNK