Recombinant human Glutathione S-transferase mu 4/GSTM4 protein
Glutathione S-transferase Mu 4 isoform 1, also known as GSTM4, is member of the glutathione s-transferase (GST) family of proteins. There are eight families of GST proteins, namely alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have a variety of functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. Recombinant human GSTM4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Glutathione S-transferase Mu 4 isoform 1, GSTM4-4, GTM4, GST class-mu 4, GST-Mu2, Glutathione S-transferase Mu 4 isoform 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
27.7 kDa (238aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Boqaards JJ., et al. (1992) Biochem J. 289 (2) :383-8.; ; Rozell B., et al. (1992) Xenobiotica. 23 (8) :835-49.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 50 mM NaCl
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_000841
Uniprot Accession Number
Q03013
Species
Human
AA Sequence
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