Recombinant human RhoC protein
RhoC, also known as rho-related GTP-binding protein RhoC, is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. It cycles between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. RhoC promotes reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Recombinant human RhoC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Rho-related GTP-binding protein RhoC, ARH9, ARHC, H9, RHOH9, Rho-related GTP-binding protein RhoC, Ras homolog family member C, Rho cDNA clone 9
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.8 (210aa) confirmed by MALDI-TOF (Real Molecular weight on SDS-PAGE will be shift up)
Additionnal Information
References & Citations
Ridley AJ.. (2006) Trends Cell Biol. 16 (10) :522-9
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.1M NaCl,1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001036144
Uniprot Accession Number
P08134
Species
Human
AA Sequence
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