Recombinant human CAB39 protein
Calcium binding protein 39, also known as CAB39, is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. Also CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization. Recombinant human CAB39, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Specifications
Product Name Alternative
Calcium binding protein 39, CGI-66, MO25, Calcium binding protein 39, CAB 39, CAB-39, MO 25, MO-25, FLJ22682
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
42 kDa (361aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Baas AF., et al. (2004) Trends Cell Biol. 14 (6) :312-9.; ; Boudeau J., et al. (2003) EMBO J. 22 (19) :5102-14.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_057373
Uniprot Accession Number
Q9Y376
Species
Human
AA Sequence
Frequently Asked Questions
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